| Primary Identifier | MGI:2151770 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Hoxb1 |
| Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Insertion of an in-frame lacZ gene and neomycin cassette into the sequences encoding the first exon. A frameshift mutation at an Sst1 site in the sequences encoding the homeobox domain was also made by cutting with the enzyme, blunt ending and ligating back together. No wild-type protein was detected in E9.5 embryos as assayed by whole mount immunohistochemisty. |
