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Allele : Apoe<tm1Lmh> apolipoprotein E; targeted mutation 1, Louis M Havekes

Primary Identifier  MGI:2152302 Allele Type  Targeted
Attribute String  Null/knockout Gene  Apoe
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A hygromycin B resistance cassette replaced exons 1, 2, and part of 3 of the gene. Northern blots of liver from homozygous mutant mice showed no detectable transcript. Western blots from homozygous mutant mice showed no detectable protein.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Apoe<0>,
  • Apoe<0>,
  • apoe-,
  • apoe-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

40 Publication categories