| First Author | El Yacoubi M | Year | 2005 |
| Journal | Eur J Pharmacol | Volume | 519 |
| Issue | 3 | Pages | 290-1 |
| PubMed ID | 16129427 | Mgi Jnum | J:104141 |
| Mgi Id | MGI:3611230 | Doi | 10.1016/j.ejphar.2005.07.022 |
| Citation | El Yacoubi M, et al. (2005) Reduced appetite for caffeine in adenosine A(2A) receptor knockout mice. Eur J Pharmacol 519(3):290-1 |
| abstractText | Adenosine A(2A) receptor knockout mice (A(2A)R KO) were compared to wild-type controls (A(2A)R WT) in a caffeine intake paradigm. When mice had ad libitum access to caffeine (0.3 g/l) and water in a two-bottle paradigm for 12 consecutive days, adenosine A(2A)R KO mice drank less caffeinated solution, demonstrating a reduced appetite for caffeine as compared to adenosine A(2A)R WT mice. These data reveal an important role for the adenosine A(2A) receptor in the appetitive properties of caffeine. |
