Primary Identifier | MGI:2152587 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Map2 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Insertion of a neomycin resistance cassette disrupted the exon that encodes the first microtubule-binding repeat. This exon corresponds to exon 15 of the human MAP2 gene. Western analysis did not detect protein in brain of eight week old homozygous mutant mice. |