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Allele : Matn1<tm1Ref> matrilin 1, cartilage matrix protein; targeted mutation 1, Reinhard Fassler

Primary Identifier  MGI:2153051 Allele Type  Targeted
Attribute String  Null/knockout Gene  Matn1
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A genomic fragment containing part of exon 3 and exons 4-6 was replaced by a neomycin resistance cassette. Northern blot analysis of total RNA derived from limb and cartilages demonstrated an absence of transcript in homozygous mice. Immunohistochemistry and Western blot analyses confirmed the lack of the protein in the cartilage of homozygous mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Crtm -,
  • Crtm -,
  • Matn1<->,
  • Matn1<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories