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Allele : Fgfr2<tm1Dsn> fibroblast growth factor receptor 2; targeted mutation 1, Clive Dickson

Primary Identifier  MGI:2153810 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Fgfr2
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  LoxP sites were inserted flanking exon IIIb as follows: A loxP flanked neomycin reistance cassette was inserted in the intron 3' to exon IIIb and an additional loxP site was inserted into the intron 5' to exon IIIb. Correctly targeted ES cells were transiently transfected with a vector expressing Cre recombinase, and lines were selected that retained exon IIIb with flanking loxP sites, and used to inject blastocysts.
  • mutations:
  • Insertion
  • synonyms:
  • Fgfr2-IIIb<flox>,
  • Fgfr2-IIIb<flox>,
  • Fgfr2(IIIb)<-cond>,
  • Fgfr2(IIIb)<-cond>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

16 Publication categories