| Primary Identifier | MGI:2153355 | Allele Type | Targeted |
| Attribute String | Humanized sequence | Gene | Fgfr1 |
| Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Derivative of Fgfr1tm2Cxd. A point mutation was introduced into exon 7 that altered codon 250 from one encoding proline to one encoding arginine (P250R). This mutation corresponds to a known human mutation in this gene that is a cause of Pfeiffer syndrome. A loxP flanked neomycin cassette in intron 6 was removed via Cre mediated recombination leaving one loxP site. |
