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Allele : Mnek1a<CAST/Ei> modifier of Nek1 (NIMA-related expressed kinase 1), kidney weight and hematocrit; CAST/Ei

Primary Identifier  MGI:2154232 Allele Type  QTL
Gene  Mnek1a Inheritance Mode  Recessive
Strain of Origin  CAST/Ei Is Recombinase  false
Is Wild Type  false
description  Mnek1a interacts with a locus near D10Mit40 (29 cM). Homozygosity for CAST/EiJ at Mnek1a and D10Mit40 significantly increases kidney weight. Mnek1a also interacts with a locus near D4Mit11 (57.4 cM). Homozygosity for CAST/EiJ-derived alleles at Menk1a and C57BL/6J-derived alleles at D4Mit11 significantly decreases hematocrit values.
molecularNote  This allele confers increased kidney weight and decreased hematocrit values compared to C57BL/6J.
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories