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Publication : Quantitative trait loci implicated in corpus callosum midsagittal area in mice.

First Author  Roy IL Year  1998
Journal  Brain Res Volume  811
Issue  1-2 Pages  173-6
PubMed ID  9804947 Mgi Jnum  J:51052
Mgi Id  MGI:1314530 Doi  10.1016/s0006-8993(98)00975-5
Citation  Roy IL, et al. (1998) Quantitative trait loci implicated in corpus callosum midsagittal area in mice. Brain Res 811(1-2):173-6
abstractText  The midsagittal area of the corpus callosum expressed as the percentage of the hemispheric surface is smaller in the NZB/BlNJ than in the C57BL/6By inbred strain of mice. We performed a QTL mapping analysis using 284 F2s. Two loci linked to this measure were found: the CCrSQTL1 and CCrSQTL2 at 87 and 67 centiMorgans from the centromere on chromosomes 1 and 4 respectively. The two loci interacted significantly. The total source of genetic variation contributed to 25% of the observed variance.
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