First Author | Roy IL | Year | 1998 |
Journal | Brain Res | Volume | 811 |
Issue | 1-2 | Pages | 173-6 |
PubMed ID | 9804947 | Mgi Jnum | J:51052 |
Mgi Id | MGI:1314530 | Doi | 10.1016/s0006-8993(98)00975-5 |
Citation | Roy IL, et al. (1998) Quantitative trait loci implicated in corpus callosum midsagittal area in mice. Brain Res 811(1-2):173-6 |
abstractText | The midsagittal area of the corpus callosum expressed as the percentage of the hemispheric surface is smaller in the NZB/BlNJ than in the C57BL/6By inbred strain of mice. We performed a QTL mapping analysis using 284 F2s. Two loci linked to this measure were found: the CCrSQTL1 and CCrSQTL2 at 87 and 67 centiMorgans from the centromere on chromosomes 1 and 4 respectively. The two loci interacted significantly. The total source of genetic variation contributed to 25% of the observed variance. |