| First Author | Ruivenkamp CA | Year | 2003 |
| Journal | Oncogene | Volume | 22 |
| Issue | 46 | Pages | 7258-60 |
| PubMed ID | 14562056 | Mgi Jnum | J:86054 |
| Mgi Id | MGI:2678629 | Doi | 10.1038/sj.onc.1207096 |
| Citation | Ruivenkamp CA, et al. (2003) Five new mouse susceptibility to colon cancer loci, Scc11-Scc15. Oncogene 22(46):7258-60 |
| abstractText | Although several genes causing familial cancer syndromes have been identified, susceptibility to sporadic cancer remains unsolved. Animal experiments have demonstrated a large number of quantitative trait loci affecting cancer susceptibility. Previously, we described in mouse strain CcS-19/Dem five susceptibility to colon cancer (Scc) loci, Scc1-Scc5 controlling tumor numbers. In the present study, we performed an independent identical mouse cross using a distinct carcinogen, azoxymethane, to induce colon tumors. We confirmed all five originally described Scc loci and detected five additional new Scc loci; Scc11-Scc15. All these loci were detected in two-way interactions.Oncogene (2003) 22, 7258-7260. doi:10.1038/sj.onc.1207096 |
