Primary Identifier | MGI:2154521 | Allele Type | Targeted |
Gene | Cdk4 | Transmission | Germline |
Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> | Is Recombinase | false |
Is Wild Type | false |
description | Phenotypic Similarity to Human Syndrome: Melanoma (J:189221) |
molecularNote | This allele is a derivative of Cdk4tm1Bbd in which the neomycin resistance cassette was deleted via Cre-mediated recombination in the germ line. These mice express comparable levels of mutant protein to wild-type levels. |