| First Author | Mori N | Year | 1995 |
| Journal | Genomics | Volume | 30 |
| Issue | 3 | Pages | 553-7 |
| PubMed ID | 8825642 | Mgi Jnum | J:30582 |
| Mgi Id | MGI:78081 | Doi | 10.1006/geno.1995.1276 |
| Citation | Mori N, et al. (1995) Apoptosis susceptibility genes on mouse chromosome 9 (Rapop2) and chromosome 3 (Rapop3). Genomics 30(3):553-7 |
| abstractText | The strain distribution pattern of susceptibility to thymocyte apoptosis induced by ionizing radiation in 20 CcS/Dem recombinant congenic (RC) strains derived from the strains BALB/cHeA (susceptible) and STS/A (resistant) indicates that this trait is controlled by several genes. Recently, we mapped a novel apoptosis susceptibility gene Rapop1 (radiation-induced apoptosis 1) to chromosome 16 (N. Mori et al., 1995, Genomics 25:604-614). In the present study, the analysis of F-2 crosses between the resistant RC strain CcS-8 and the susceptible strain BALB/ cHeA or the highly susceptible RC strain CcS-10 demonstrated two additional apoptosis susceptibility genes, Rapop2 and Rapop3, located in the proximal region of chromosome 9 and the telomeric region of chromosome 3, respectively. The possible candidate genes for these loci are discussed. (C) 1995 Academic Press, Inc. |
