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Allele : Malrd1<C57BL/6ByJ> MAM and LDL receptor class A domain containing 1; C57BL/6By

Primary Identifier  MGI:2154956 Allele Type  QTL
Attribute String  Null/knockout Gene  Malrd1
Inheritance Mode  Recessive Strain of Origin  C57BL/6ByJ
Is Recombinase  false Is Wild Type  false
description  This allele confers decreased plasma LDL and VLDL levels compared to A/J. This allele confers increased plasma bile acid levels compared to CAST/Ei.
molecularNote  A spontaneous duplication results in a greater than 33 kb insertion containing a second copy of exons 21, 22 and 23. This duplication introduces a frame shift and premature stop codon. Northern blot analysis confirmed the absence of transcript expression.
  • mutations:
  • Duplication
  • synonyms:
  • Diet1<->,
  • Diet1<->
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1 Feature

Genome

0 Expresses

1 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories