Primary Identifier | MGI:2155448 | Allele Type | QTL |
Gene | Tmevd2 | Inheritance Mode | Not Specified |
Strain of Origin | DBA/2J | Is Recombinase | false |
Is Wild Type | false |
description | This is a susceptibility allele (J:43978). Theiler's murine encephalomyelitis virus (TMEV), introduced into the central nervous system (CNS), causes CNS demyelination. The H2-D1 region and at least two non-H2 loci are involved: Tmevd1 on Chr 6, and this second locus, Tmevd2, which has been localized on Chr 3 using the susceptible DBA/2 and resistant C57BL/6 strains and the BXD recombinant inbred strain panel (J:10200). |