|  Help  |  About  |  Contact Us

Allele : Abcb1b<tm2Bor> ATP-binding cassette, sub-family B member 1B; targeted mutation 2, Piet Borst

Primary Identifier  MGI:2155889 Allele Type  Targeted
Attribute String  Null/knockout Gene  Abcb1b
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A genomic fragment containing exons 3 and 4 was deleted and replaced with a neomycin selection cassette. These sequences encode the first putative transmembrane segment and flanking sequences. This mutation also introduces a frameshift and any protein produced from this allele is predicted to be nonfunctional.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • mdr1b-,
  • mdr1b-
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories