| Primary Identifier | MGI:2155977 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Ada |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A hygromycin selection cassette replaced a genomic fragment containing exon 4, which encodes part of the active site of the enzyme. Western blot analysis of thymus, liver and brain extracts confirmed that the protein was not detectable in homozygous mice. Activity assays demonstrated that no functional protein was made from this allele in homozygous mice. |
