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Allele : Abcc9<tm1Cfb> ATP-binding cassette, sub-family C member 9; targeted mutation 1, Charles F Burant

Primary Identifier  MGI:2155916 Allele Type  Targeted
Attribute String  Null/knockout Gene  Abcc9
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette replaced sequences encoding the first ATP binding domain and a transmembrane domain. An additional integration event 3' to the gene caused a duplication of the gene between exons 9 to 27. Northern blot analysis indicated that no transcript was detectable from this allele in RNA derived from heart or skeletal muscle in homozygous mice. No protein activity was detected in cardiac myocytes or in skeletal muscle of homozygous mice.
  • mutations:
  • Intragenic deletion,
  • Duplication,
  • Insertion
  • synonyms:
  • Sur2 -,
  • Sur2 -
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1 Feature

Genome

0 Expresses

1 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

16 Publication categories