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Allele : Adora3<tm1Jbsn> adenosine A3 receptor; targeted mutation 1, Marlene A Jacobson

Primary Identifier  MGI:2155986 Allele Type  Targeted
Attribute String  Null/knockout Gene  Adora3
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette replaced a genomic fragment containing the initiation codon through sequences encoding the third transmembrane domain and the following intron. No transcript was detectable in northern blot analysis on RNA from bone marrow-derived mast cells (BMMCs) derived from homozygous mice. Binding assays confirmed the absence of protein from BMMCs derived from homozygous mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • A3<->,
  • A3AR-,
  • A3R<->,
  • A3AR-,
  • A3R<->,
  • A3KO,
  • A3<->,
  • A3KO
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

50 Publication categories