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Allele : Itgb1<tm1Mll> integrin beta 1 (fibronectin receptor beta); targeted mutation 1, Ulrich Muller

Primary Identifier  MGI:2156945 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Itgb1
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  LoxP sites were inserted flanking the first coding exon as follows: One loxP site was inserted 5' to the exon and a loxP-flanked neomycin and thymidine kinase selection cassette was inserted 3' to the exon. The neomycin and thymidine kinase selection cassette was removed via Cre-mediated recombination in ES cells prior to creation of chimeric mice, leaving one loxP site in place of the cassette.
  • mutations:
  • Insertion
  • synonyms:
  • B1-loxP1,
  • B1-loxP1,
  • Itgbeta1<fx>,
  • beta1-flox,
  • Itgbeta1<flox>,
  • Itb1<fl>,
  • Itb1<fl>,
  • beta1-flox,
  • Itgbeta1<flox>,
  • Itgbeta1<fx>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

37 Publication categories