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Allele : Pax8<tm1Pgr> paired box 8; targeted mutation 1, Peter Gruss

Primary Identifier  MGI:2156985 Allele Type  Targeted
Attribute String  Null/knockout Gene  Pax8
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  The vector containing a neo cassette was targeted to exon 2. A thymidine kinase gene was inserted at the 3' end of the construct. This leads to complete inactivation as the putative splicing from exon 1 to exon 3 renders the codons out of frame, terminating after 11 heterologous amino acids.
  • mutations:
  • Insertion
  • synonyms:
  • Pax8-,
  • Pax8-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

4 Carried By

0 Driven By

37 Publication categories