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Allele : Coq7<tm1Hek> demethyl-Q 7; targeted mutation 1, Siegfried Hekimi

Primary Identifier  MGI:2157003 Allele Type  Targeted
Attribute String  Null/knockout Gene  Coq7
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance cassette replaced part of exon II and all of exons III and IV. Northern blot analysis using a full length cDNA probe did not detect transcript in homozygous mutant E11.5 embryos. Immunoblot analysis using a polyclonal antibody detected a 21kDa band in liver and brain that was reduced by 50% in heterozygote mice compared with wild-type mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • mclk1-,
  • mclk1-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

13 Publication categories