| Primary Identifier | MGI:2157003 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Coq7 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A neomycin resistance cassette replaced part of exon II and all of exons III and IV. Northern blot analysis using a full length cDNA probe did not detect transcript in homozygous mutant E11.5 embryos. Immunoblot analysis using a polyclonal antibody detected a 21kDa band in liver and brain that was reduced by 50% in heterozygote mice compared with wild-type mice. |