Primary Identifier | MGI:2157396 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Il1b |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A lacZ-PGK-neomycin resistance cassette replaced part of exon 3, all of exon 4, and part of exon 5, including sequences encoding the amino terminus of the mature protein. Northern blot analysis of activated peritoneal macrophages did not detect transcript in homozygous mutant mice. |