First Author | Roy S | Year | 2019 |
Journal | J Allergy Clin Immunol | Volume | 144 |
Issue | 2 | Pages | 603-606 |
PubMed ID | 31077686 | Mgi Jnum | J:326598 |
Mgi Id | MGI:6783910 | Doi | 10.1016/j.jaci.2019.04.024 |
Citation | Roy S, et al. (2019) beta-Arrestin2 expressed in mast cells regulates ciprofloxacin-induced pseudoallergy and IgE-mediated anaphylaxis. J Allergy Clin Immunol 144(2):603-606 |
abstractText | The adapter protein beta-arrestin2 inhibits Mrgprb2 and FcepsilonRI-mediated mast cell degranulation to attenuate pseudo-allergy and anaphylaxis. Thus, targeting beta-arrestin2 in mast cells could provide novel therapeutic options for modulating pseudo-allergy and anaphylaxis. |