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Allele : Npr1<tm1Mae> natriuretic peptide receptor 1; targeted mutation 1, Nobuyo Maeda

Primary Identifier  MGI:2158387 Allele Type  Targeted
Attribute String  Null/knockout Gene  Npr1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A genomic fragment containing exon 1 and part of intron 1 was replaced with a neomycin selection cassette. The deleted sequences encode 237 amino acids from the N-terminal region of the corresponding protein. Western blot analysis on kidney membranes derived from homozygous mice demonstrated that no detectable protein is produced from this allele.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Npr1<->,
  • Npr1<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

32 Publication categories