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Allele : Prf1<tm1Clrk> perforin 1 (pore forming protein); targeted mutation 1, William R Clark
Primary Identifier  MGI:2158403 Allele Type  Targeted
Attribute String  Null/knockout Gene  Prf1
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance gene was inserted into exon 2. Western blot analysis on splenocytes derived from homozygous mice demonstrated that no detectable protein is produced from this allele.
  • mutations:
  • Insertion
  • synonyms:
  • perforin-less (-),
  • PKO,
  • pfp<->,
  • perforin-less (-),
  • pfp<->,
  • PKO
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

72 Publication categories





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