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Allele : Igh-8<tm1Schr> immunoglobulin heavy chain 8 (heavy chain of IgG3); targeted mutation 1, John R Schreiber
Primary Identifier  MGI:2158494 Allele Type  Targeted
Attribute String  Null/knockout Gene  Igh-8
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A 54 bp DNA fragment of exon CH1 was replaced with a neomycin selection cassette. ELISA assays demonstrated that no soluble IgG3 protein was detectable in serum derived from homozygous mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • IgG3-,
  • Igh-8<tm1Sch>,
  • IgG3-,
  • Igh-8<tm1Sch>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

6 Publication categories





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