Primary Identifier | MGI:2158497 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Bmpr1b |
Transmission | Germline | Strain of Origin | 129S/SvEv-Gpi1<c> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A genomic fragment containing the first coding exon was replaced with a neomycin selection cassette. RT-PCR analysis on total embryo RNA from homozygous embryos demonstrated that an aberrant transcript is produced from this allele, but the authors predict that no functional protein can be produced. |