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Allele : Blm<tm2Brd> Bloom syndrome, RecQ like helicase; targeted mutation 2, Allan Bradley

Primary Identifier  MGI:2158669 Allele Type  Targeted
Attribute String  Null/knockout Gene  Blm
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase  false Is Wild Type  false
description  Other alleles of this gene serve as models for Bloom Syndrome. This allele results in embryonic lethality and could not be studied in this context.
molecularNote  Three copies of a targeting vector inserted into the gene. The authors predict that an aberrant transcript containing 4 copies of exon 3 is made. However, western blot analysis on protein extracts of testes demonstrated that no detectable protein was produced from this allele.
  • mutations:
  • Insertion
  • synonyms:
  • Blm<m2>,
  • Blm<m2>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories