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Allele : Bid<tm1Sjk> BH3 interacting domain death agonist; targeted mutation 1, Stanley J Korsmeyer

Primary Identifier  MGI:2158671 Allele Type  Targeted
Attribute String  Null/knockout Gene  Bid
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  A 4.2 kb genomic fragment containing exons 1, 2 and part of 3 was replaced with a neomycin selection cassette inserted in reverse transcriptional orientation to the gene. The deleted sequences encode the BH3 domain of the protein. Western blot analysis on spleen and thymus samples derived from homozygous mice demonstrated that no detectable protein is produced from this allele.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Bid-,
  • Bid-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

78 Publication categories