|  Help  |  About  |  Contact Us

Allele : Irs2<tm1Mfw> insulin receptor substrate 2; targeted mutation 1, Morris F White

Primary Identifier  MGI:2158686 Allele Type  Targeted
Attribute String  Null/knockout Gene  Irs2
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector containing a PGK-neomycin cassette replaced the entire gene. Lack of protein was demonstrated in liver and muscle extracts by Western analysis in homozygous mutant animals.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Irs2<->,
  • Irs2<->
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

64 Publication categories