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Allele : Sema3a<tm1.1Tyag> sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A; targeted mutation 1.1, Takeshi Yagi
Primary Identifier  MGI:2158944 Allele Type  Targeted
Attribute String  Null/knockout Gene  Sema3a
Inheritance Mode  Recessive Transmission  Germline
Strain of Origin  (C57BL/6NCrlj x CBA/JNCrlj)F1 Is Recombinase  false
Is Wild Type  false
description  Homozygous embryos are largely viable after birth but at 4 weeks after birth are about half the body weight of wild-type and have abnormalities in peripheral nerve projection.
molecularNote  This allele was generated from Sema3atm1Tyag by transient cre expression in TT-2 cells. Recombination produced three alleles, Sema3atm1.1Tyag, Sema3atm1.2Tyag and Sema3atm1.3Tyag. Sema3tm1.1Tyag has had the first exon, including the initiation codon, deleted.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • semaphorin III/D null,
  • semaphorin III/D null,
  • Sema3a<->,
  • Sema3a<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

49 Publication categories





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