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Allele : Scnn1a<tm1Rss> sodium channel, nonvoltage-gated 1 alpha; targeted mutation 1, Bernard C Rossier

Primary Identifier  MGI:2158700 Allele Type  Targeted
Attribute String  Null/knockout Gene  Scnn1a
Transmission  Germline Strain of Origin  129P2/OlaHsd-Hprt1<b-m3>
Is Recombinase  false Is Wild Type  false
molecularNote  A genomic fragment containing part of exon 1 and sequences encoding the first transmembrane loop and most of the ectocytoplasmic loop was replaced with a neomycin selection cassette. RT-PCR analysis on samples derived from lung, liver and kidney tissue of homozygous mice confirmed that no detectable transcript is produced from this allele.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • alphaENaC -,
  • Scnn1a<tm1>,
  • alphaENaC -,
  • Scnn1a<tm1>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

16 Publication categories