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Allele : C3<tm1Hrc> complement component 3; targeted mutation 1, Harvey R Colten

Primary Identifier  MGI:2158703 Allele Type  Targeted
Attribute String  Null/knockout Gene  C3
Transmission  Germline Strain of Origin  129/Sv
Is Recombinase  false Is Wild Type  false
description  ES cell line = RW4 (129X1/SvJ) or D3 (129S2/SvPas).
molecularNote  A genomic fragment containing 2.3 kb of the 5' flanking region and the first 105 bp of exon 1 was replaced with a neomycin selection cassette. Northern blot analysis on liver RNA derived from homozygous mice demonstrated that no detectable transcript was produced in this tissue; however, a full length transcript was detected in lung, kidney, epididymal fat tissue, spleen and heart.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • C3-,
  • C3-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

83 Publication categories