Primary Identifier | MGI:2158703 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | C3 |
Transmission | Germline | Strain of Origin | 129/Sv |
Is Recombinase | false | Is Wild Type | false |
description | ES cell line = RW4 (129X1/SvJ) or D3 (129S2/SvPas). |
molecularNote | A genomic fragment containing 2.3 kb of the 5' flanking region and the first 105 bp of exon 1 was replaced with a neomycin selection cassette. Northern blot analysis on liver RNA derived from homozygous mice demonstrated that no detectable transcript was produced in this tissue; however, a full length transcript was detected in lung, kidney, epididymal fat tissue, spleen and heart. |