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Allele : Cfb<tm1Mbo> complement factor B; targeted mutation 1, Marina Botto

Primary Identifier  MGI:2158706 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Cfb
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A 6 kb genomic fragment containing part of exon 1 through exon 18 was replaced with a promoterless lacZ gene linked to a neomycin selection cassette. Northern blot analysis on liver RNA derived from homozygous mice demonstrated that no detectable transcript was produced from this allele. Activity assays on serum derived from homozygous mice confirmed that no functional protein was made.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • C2/fB KO,
  • Bf/C2<->,
  • C2/FB-,
  • B/C2<->,
  • C2/fB KO,
  • Bf/C2<->,
  • B/C2<->,
  • C2/FB-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

24 Publication categories