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Allele : Gulo<tm1Mae> gulonolactone (L-) oxidase; targeted mutation 1, Nobuyo Maeda

Primary Identifier	MGI:2158350	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Gulo
Transmission	Germline	Strain of Origin	Not Specified
Is Recombinase	false	Is Wild Type	false

molecularNote

A genomic fragment containing exons 3 and 4 was replaced with a neomycin selection cassette. Northern blot analysis confirmed that no detectable transcript is produced from this allele in liver of homozygous mice.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
Gulo<tm1Unc>,
gulo-,
Gulo<tm1Unc>,
gulo-

earliestPublication:
Maeda N, et al. (2000) Aortic wall damage in mice unable to synthesize ascorbic acid. Proc Natl Acad Sci U S A 97(2):841-6

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

2 Carried By

0 Driven By

48 Publication categories

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