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Allele : Mecp2<tm1Jae> methyl CpG binding protein 2; targeted mutation 1, Rudolf Jaenisch

Primary Identifier  MGI:2158353 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Mecp2
Transmission  Germline Strain of Origin  (C57BL/6 x 129S4/SvJae)F1
Is Recombinase  false Is Wild Type  false
molecularNote  LoxP sites were inserted flanking exon 3 as follows: A single loxP site was inserted 5' to exon 3 and a loxP-flanked hygromycin and thymidine kinase selection cassette was inserted 3' to exon 3. The selection cassette was removed in ES cells by Cre-mediated recombination prior to the production of chimeric mice, leaving a single loxP site in place of the selection cassette.
  • mutations:
  • Insertion
  • synonyms:
  • Mecp<2lox>,
  • Mecp<2lox>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

37 Publication categories