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Allele : Mecp2<tm1.1Jae> methyl CpG binding protein 2; targeted mutation 1.1, Rudolf Jaenisch

Primary Identifier  MGI:2158354 Allele Type  Targeted
Attribute String  Null/knockout Gene  Mecp2
Transmission  Germline Strain of Origin  (C57BL/6 x 129S4/SvJae)F1
Is Recombinase  false Is Wild Type  false
molecularNote  This allele is a derivative of Mecp2tm1Jae in which exon 3 is deleted by Cre mediated recombination in a germline transmissible event. Mice carrying Mecp2tm1Jae were mated to transgenic mice carrying a cre transgene under the control of a nestin promoter. This promoter was active in the male and female germline as well as the brain, and progeny of the cross were screened for deletion of exon 3.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Mecp<1lox>,
  • Mecp2<tm1-1Jae>,
  • Mecp2<tm1-1Jae>,
  • Mecp<1lox>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

99 Publication categories