| Primary Identifier | MGI:2158764 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Il6 |
| Transmission | Germline | Strain of Origin | 129S/SvEv-Gpi1<c> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A genomic fragment containing exons 1, 2 and 3 was replaced with a neomycin selection cassette. Northern blot analysis on RNA derived from LPS-induced splenocytes of homozygous mice demonstrated that no detectable transcript was produced from this allele. ELISA assays confirmed that no detectable protein was produced in homozygous mice. |
