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Allele : Nos2<tm1Mrl> nitric oxide synthase 2, inducible; targeted mutation 1, Merck Research Laboratory

Primary Identifier  MGI:2158791 Allele Type  Targeted
Attribute String  Null/knockout Gene  Nos2
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette replaced a genomic fragment containing 585 bp of the promoter and exons 1-4. Northern blot analysis on RNA derived from various tissues of homozygous mice demonstrated that no detectable transcript was produced from this allele. However, a transcript has been reported from sequence downstream from exon 4.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • iNOS KO,
  • Nos2<tm1Ntn>,
  • iNOS KO,
  • iNOS-,
  • Nos2<tm1Ntn>,
  • iNOS-,
  • NOS2-,
  • NOS2-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

6 Carried By

0 Driven By

159 Publication categories