Primary Identifier | MGI:2158791 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Nos2 |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A neomycin selection cassette replaced a genomic fragment containing 585 bp of the promoter and exons 1-4. Northern blot analysis on RNA derived from various tissues of homozygous mice demonstrated that no detectable transcript was produced from this allele. However, a transcript has been reported from sequence downstream from exon 4. |