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Allele : Gpx1<tm1Ysh> glutathione peroxidase 1; targeted mutation 1, Ye-Shih Ho

Primary Identifier  MGI:2158814 Allele Type  Targeted
Attribute String  Null/knockout Gene  Gpx1
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Insertion of a neomycin resistance cassette disrupted exon 2 of the gene. Northern blots of total RNA isolated from brain, heart, kidney, liver, and lung of homozygous mutant mice showed no detectable transcript of the targeted gene when probed with an a gene-specific cDNA probe.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Gpx1-,
  • Gpx1-,
  • GSHPx-1-deficient,
  • GpX-1 KO,
  • GPX1 KO,
  • GpX-1 KO,
  • GSHPx-1-deficient,
  • GPX1 KO
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

5 Carried By

0 Driven By

86 Publication categories