| Help | About | Contact Us

Allele : Anxa7<tm1Pll> annexin A7; targeted mutation 1, Harvey B Pollard

Primary Identifier	MGI:2159005	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Anxa7
Transmission	Germline	Strain of Origin	Not Specified
Is Recombinase	false	Is Wild Type	false

molecularNote

A neomycin selection cassette replaced a genomic fragment containing exon 6. Western blot analysis on pancreatic tissue lysates of homozygous mice confirmed that levels of the encoded protein were reduced in heterozygotes compared to wild-type.

mutations:
Intragenic deletion,
Insertion

cellLines:
Not Specified

synonyms:
anx7 -,
anx7 -

earliestPublication:
Srivastava M, et al. (1999) Defects in inositol 1,4,5-trisphosphate receptor expression, Ca(2+) signaling, and insulin secretion in the anx7(+/-) knockout mouse. Proc Natl Acad Sci U S A 96(24):13783-8

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

7 Publication categories

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/report.do?id=74243214

MouseMine