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Allele : Gja1<tm1Dlg> gap junction protein, alpha 1; targeted mutation 1, Brian R Duling

Primary Identifier  MGI:2159007 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Gja1
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase  false Is Wild Type  false
molecularNote  LoxP sites were inserted flanking exon 2. A neomycin selection cassette and thymidine kinase gene that were also inserted 3' to the loxP sites were removed by transient cre recombinase expression in ES cells prior to the production of chimeric mice. Western blot and immunohistochemistry analysis on homozygous mice confirmed that there were no detectable changes in the expression of the encoded protein.
  • mutations:
  • Insertion
  • synonyms:
  • Cx43<fl>,
  • Cx43<fl>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

62 Publication categories