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Publication : Passive stiffness is increased in soleus muscle of desmin knockout mouse.

First Author  Anderson J Year  2001
Journal  Muscle Nerve Volume  24
Issue  8 Pages  1090-2
PubMed ID  11439386 Mgi Jnum  J:116330
Mgi Id  MGI:3694036 Doi  10.1002/mus.1115
Citation  Anderson J, et al. (2001) Passive stiffness is increased in soleus muscle of desmin knockout mouse. Muscle Nerve 24(8):1090-2
abstractText  The effects of an absence of desmin on passive stiffness of skeletal muscle were analyzed using soleus muscles from desmin knockout mice. Stiffness was evaluated by analyzing the passive tension induced by a ramp-and-hold extension test. This test showed that passive resistance to stretch was largely increased for muscles lacking desmin. This study could facilitate interpretation of changes in muscle mechanics observed in humans affected by desmin-related myopathies.
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