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Allele : Aifm1<tm1Pngr> apoptosis-inducing factor, mitochondrion-associated 1; targeted mutation 1, Josef M Penninger

Primary Identifier  MGI:2159372 Allele Type  Targeted
Attribute String  Null/knockout Gene  Aifm1
Transmission  Cell Line Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
description  Cells fail to establish chimeric mice in a rag1 null or C57BL/6 background; however, ES cells can differentiate into all three germ layers. J:68434
molecularNote  A neomycin resistance cassette replaced a genomic fragment containing exon 3. Northern and western blotting confirmed that no transcript or protein was expressed from this allele (data not shown).
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • aif<->,
  • aif<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories