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Allele : Ccl2<tm1Rol> C-C motif chemokine ligand 2; targeted mutation 1, Barrett J Rollins

Primary Identifier  MGI:2175911 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ccl2
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A small deletion and an in frame stop codon were created in exon 1. A PGK-neomycin resistance cassette was also inserted into exon 2. Secreted protein was not detected in stimulated peritoneal macrophages from homozygous mutant mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • CCL2KO,
  • CCL2<->,
  • MCP-1-,
  • (MCP)1-,
  • MCP-1KO,
  • CCL2KO,
  • CCL2<->,
  • MCP-1KO,
  • (MCP)1-,
  • Scya2-,
  • Scya2-,
  • MCP-1-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

5 Carried By

0 Driven By

263 Publication categories