First Author | Dessing MC | Year | 2006 |
Journal | Infect Immun | Volume | 74 |
Issue | 12 | Pages | 7021-3 |
PubMed ID | 16982835 | Mgi Jnum | J:115915 |
Mgi Id | MGI:3692461 | Doi | 10.1128/IAI.00977-06 |
Citation | Dessing MC, et al. (2006) Monocyte chemoattractant protein 1 does not contribute to protective immunity against pneumococcal pneumonia. Infect Immun 74(12):7021-3 |
abstractText | To determine the role of monocyte chemoattractant protein 1 (MCP-1) during pneumococcal pneumonia, MCP-1 knockout and wild-type mice were infected with Streptococcus pneumoniae. Pulmonary MCP-1 levels were strongly correlated to bacterial loads in wild-type mice. However, MCP-1 knockout and wild-type mice were indistinguishable with respect to bacterial growth, inflammatory responses, and lethality. |