First Author | Inoue D | Year | 2016 |
Journal | Cancer Cell | Volume | 30 |
Issue | 3 | Pages | 371-373 |
PubMed ID | 27622329 | Mgi Jnum | J:234979 |
Mgi Id | MGI:5792586 | Doi | 10.1016/j.ccell.2016.08.013 |
Citation | Inoue D, et al. (2016) Modeling SF3B1 Mutations in Cancer: Advances, Challenges, and Opportunities. Cancer Cell 30(3):371-3 |
abstractText | In this issue of Cancer Cell, Obeng et al. identify the consequences of expressing the most common mutation in the spliceosomal gene SF3B1 on hematopoiesis. The knockin mouse model described represents a valuable tool to dissect the effects of SF3B1 mutations on transformation, splicing, and less well-characterized functions of SF3B1. |