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Publication : Genetic targeting of chemical indicators in vivo.

First Author  Yang G Year  2015
Journal  Nat Methods Volume  12
Issue  2 Pages  137-9
PubMed ID  25486061 Mgi Jnum  J:222844
Mgi Id  MGI:5645757 Doi  10.1038/nmeth.3207
Citation  Yang G, et al. (2015) Genetic targeting of chemical indicators in vivo. Nat Methods 12(2):137-9
abstractText  Fluorescent protein reporters have become the mainstay for tracing cellular circuitry in vivo but are limited in their versatility. Here we generated Cre-dependent reporter mice expressing the Snap-tag to target synthetic indicators to cells. Snap-tag labeling worked efficiently and selectively in vivo, allowing for both the manipulation of behavior and monitoring of cellular fluorescence from the same reporter.
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