|  Help  |  About  |  Contact Us

Allele : Tg(Ins2-cre)25Mgn transgene insertion 25, Mark A Magnuson
Primary Identifier  MGI:2176227 Allele Type  Transgenic
Attribute String  Recombinase Gene  Tg(Ins2-cre)25Mgn
Strain of Origin  (C57BL/6 x DBA)F2 Is Recombinase  true
Is Wild Type  false
molecularNote  This transgene expresses Cre recombinase with a human growth hormone polyadenylation signal under the control of the rat insulin promoter (Ins2), which is active in pancreatic beta cells and in neurons of the hypothalamus. 9 copies of the transgene are estimated to be present. Transgene insertion occurred on Chr 7, causing a 17400 bp duplication.
  • mutations:
  • Insertion,
  • Duplication
  • synonyms:
  • Ins-Cre,
  • M line,
  • TgN(ins2-Cre)25Mgn,
  • RIP Cre,
  • Rip-cre,
  • RIP Cre,
  • [RIP]-Cre,
  • RIP2-cre,
  • RIPCre,
  • TgN(ins2-Cre)25Mgn,
  • Rip-cre,
  • RIP-Cre,
  • RIP-Cre,
  • RIP2-cre,
  • Ins2cre,
  • RIP2<Cre>,
  • RIPCre,
  • RIP2<Cre>,
  • Ins2cre,
  • Ins-Cre,
  • [RIP]-Cre,
  • M line
Paste the following link
Quick Links:
SummaryGenomePhenotypeOther
 
Quick Links:
SummaryGenomePhenotypeOther
 
Lists
This Allele isn't in any lists. Upload a list.

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

8 Carried By

1 Driven By

298 Publication categories





MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom